Biosimilar Research Grade ELISA

Biosimilar Research Grade ELISA kits are designed to provide high-quality, reproducible assays for the characterization and analysis of biosimilars in the early stages of research and development. These kits help ensure that biosimilar candidates exhibit comparable quality, safety, and efficacy to the original biologic products.

Key Features

  • High Sensitivity and Specificity:
    • Capable of detecting low concentrations of biosimilar proteins, ensuring accurate characterization and comparison to reference biologics.
  • Quantitative Analysis:
    • Provides precise measurement of protein concentrations, enabling detailed assessment of biosimilar quality.
  • Reproducibility:
    • Designed to deliver consistent results across multiple assays and batches, essential for reliable biosimilar development.
  • Comprehensive Kits:
    • Includes all necessary reagents, such as capture and detection antibodies, standards, and substrates, to streamline the assay process.

Methodology

  • Sample Preparation:
    • Biosimilar samples are prepared in appropriate buffers to ensure optimal binding and detection.
  • Plate Coating:
    • Plates are pre-coated with specific capture antibodies that bind to the target biosimilar protein.
  • Binding and Detection:
    • Samples are added to the coated plates, allowing the target protein to bind to the capture antibodies.
    • Detection antibodies, conjugated to enzymes like horseradish peroxidase (HRP) or alkaline phosphatase (AP), are added. These antibodies bind to the captured protein, forming a sandwich complex.
    • A substrate is introduced, and the enzyme reaction generates a measurable signal.
  • Signal Measurement:
    • The signal intensity, typically measured as absorbance, fluorescence, or luminescence, correlates with the concentration of the biosimilar protein in the sample.
  • Data Analysis:
    • The results are analyzed using standard curves and software to quantify the biosimilar protein concentration and compare it to reference standards.

Applications

  • Early-Stage Research:
    • Used in the initial characterization of biosimilar candidates, helping researchers assess their comparability to reference biologics.
  • Quality Control:
    • Ensures consistency and quality of biosimilar production batches during the development phase.
  • Regulatory Submissions:
    • Provides robust data to support regulatory filings, demonstrating the biosimilar's similarity to the original biologic.

Advantages

  • Enhanced Sensitivity and Specificity:
    • Ensures accurate detection and quantification of biosimilar proteins, critical for early-stage research.
  • Reliable and Reproducible:
    • Consistent performance across assays and batches, essential for dependable biosimilar development.
  • Comprehensive and Convenient:
    • All-inclusive kits simplify the assay process, reducing variability and enhancing efficiency.
AffiADA® Vedolizumab Biosimilar - Research Grade
CAT# AFG-FMN-198
Size: 500 µg
576.25 576.25 USD
AffiADA® Ustekinumab Biosimilar - Research Grade
CAT# AFG-FMN-197
Size: 500 µg
576.25 576.25 USD
AffiADA® Secukinumab Biosimilar - Research Grade
CAT# AFG-FMN-196
Size: 500 µg
576.25 576.25 USD
AffiADA® Ramucirumab Biosimilar - Research Grade
CAT# AFG-FMN-195
Size: 500 µg
576.25 576.25 USD
AffiADA® Ranibizumab Biosimilar - Research Grade
CAT# AFG-FMN-194
Size: 500 µg
576.25 576.25 USD
AffiADA® Pertuzumab Biosimilar - Research Grade
CAT# AFG-FMN-193
Size: 500 µg
576.25 576.25 USD
576.25 576.25 USD
AffiADA® Panitumumab Biosimilar - Research Grade
CAT# AFG-FMN-191
Size: 500 µg
576.25 576.25 USD
AffiADA® Ofatumumab Biosimilar - Research Grade
CAT# AFG-FMN-190
Size: 500 µg
576.25 576.25 USD
576.25 576.25 USD
AffiADA® Ipilimumab Biosimilar - Research Grade
CAT# AFG-FMN-188
Size: 500 µg
576.25 576.25 USD
AffiADA® Evolocumab Biosimilar - Research Grade
CAT# AFG-FMN-187
Size: 500 µg
576.25 576.25 USD
AffiADA® Etanercept Biosimilar - Research Grade
CAT# AFG-FMN-186
Size: 500 µg
576.25 576.25 USD
AffiADA® Daratumumab Biosimilar - Research Grade
CAT# AFG-FMN-185
Size: 500 µg
576.25 576.25 USD
AffiADA® Denosumab Biosimilar - Research Grade
CAT# AFG-FMN-184
Size: 500 µg
576.25 576.25 USD
576.25 576.25 USD
AffiADA® Avelumab Biosimilar - Research Grade
CAT# AFG-FMN-182
Size: 500 µg
576.25 576.25 USD
AffiADA® Alirocumab Biosimilar - Research Grade
CAT# AFG-FMN-181
Size: 500 µg
576.25 576.25 USD
AffiADA® Aflibercept Biosimilar - Research Grade
CAT# AFG-FMN-180
Size: 500 µg
576.25 576.25 USD
576.25 576.25 USD
AffiADA® Trastuzumab Biosimilar - Research Grade
CAT# AFG-FMN-178
Size: 500 µg
576.25 576.25 USD
AffiADA® Tocilizumab Biosimilar - Research Grade
CAT# AFG-FMN-177
Size: 500 µg
576.25 576.25 USD
AffiADA® Rituximab Biosimilar - Research Grade
CAT# AFG-FMN-176
Size: 500 µg
576.25 576.25 USD
AffiADA® Omalizumab Biosimilar - Research Grade
CAT# AFG-FMN-175
Size: 500 µg
576.25 576.25 USD
AffiADA® Nivolumab Biosimilar - Research Grade
CAT# AFG-FMN-174
Size: 500 µg
576.25 576.25 USD
AffiADA® Nimotuzumab Biosimilar - Research Grade
CAT# AFG-FMN-173
Size: 500 µg
576.25 576.25 USD
AffiADA® Matuzumab Biosimilar - Research Grade
CAT# AFG-FMN-172
Size: 500 µg
576.25 576.25 USD
AffiADA® Infliximab Biosimilar - Research Grade
CAT# AFG-FMN-171
Size: 500 µg
576.25 576.25 USD
AffiADA® Eculizumab Biosimilar - Research Grade
CAT# AFG-FMN-170
Size: 500 µg
576.25 576.25 USD
AffiADA® Cetuximab Biosimilar - Research Grade
CAT# AFG-FMN-169
Size: 500 µg
576.25 576.25 USD
AffiADA® Bevacizumab Biosimilar - Research Grade
CAT# AFG-FMN-168
Size: 500 µg
576.25 576.25 USD
AffiADA® Alemtuzumab Biosimilar - Research Grade
CAT# AFG-FMN-167
Size: 500 µg
576.25 576.25 USD
AffiADA® Adalimumab Biosimilar - Research Grade
CAT# AFG-FMN-166
Size: 500 µg
576.25 576.25 USD